emergence of pseudomonas aeruginosa cross-infection in children with cystic fibrosis attending an iranian referral pediatric center.

Emergence of Pseudomonas aeruginosa cross-infection in children with cystic fibrosis attending an Iranian referral pediatric center

BACKGROUND AND OBJECTIVES This study was carried out with the objective of determining the genomic variability of P. aeruginosa strains isolated from patients suffering from cystic fibrosis or from environmental cultures collected from different locations in the unit they admitted. MATERIALS AND METHODS A total of 57 clinical and environmental P. aeruginosa isolates were genotyped by enteroba...

Cross infection of cystic fibrosis patients with Pseudomonas aeruginosa.

Pseudomonas Aeruginosa Infection in Cystic Fibrosis Patients

Cystic Fibrosis is an autosomal recessive genetic disease where the lung is heavily colonized by biofilm forming Pseudomonas aeruginosabacteria. Biofilm due to its thick wall and presence of extracellular polymeric substances confers bacteria with a much higher resistance against antimicrobial compounds and environmental stress. Research has revealed the presence of extracellular DNA (eDNA) in ...

Isolation and Genetic Fingerprinting of Pseudomonas aeruginosa from Iranian Patients with Cystic Fibrosis Using RAPD-PCR

Sixty four Iranian patients with cystic fibrosis (CF) were studied for colonization with Pseudomonasaeruginosa. The patient’s age ranged between 2 months to 18 years old. Twenty one patients werecolonized, 15 with non-mucoid and 6 with mucoid strains of P. aeruginosa. The colonization rateincreased with age and the mucoid phenotype was only recovered from the older patients. A...

Acquisition of Pseudomonas aeruginosa in children with cystic fibrosis.

OBJECTIVE This study was pursued as an extension of a randomized clinical investigation of neonatal screening for cystic fibrosis (CF). The project included assessment of respiratory secretion cultures for pathogens associated with CF. The objective was to determine whether patients diagnosed through neonatal screening and treated in early infancy were more likely to become colonized with Pseud...

Antibiotic Susceptibility of Pseudomonas Aeruginosa Isolated from Cystic Fibrosis Patients

Abstract Background and Objective: Cystic fibrosis (CF) is an autosomal recessive genetic disease and Pseudomonas aeruginosa is one of the most common bacteria colonized in CF patients. Growing resistance of this bacterium to antibiotics now a day is a challenge of controlling infection in CF patient. In this study colonization of CF patients with Pseudomonas aeruginosa and antibiotic suscep...